Biology

1. Sigma subunit of RNA polymerase:

Initiate republication

Provides contact between ribonucleotide and DNA template

Specifies the site for transcription

Terminates transcription

Question 1 of 18

2. Genes whose products are constantly needed for cellular activity are called:

Regulator genes

House keeping genes

Smart gene

Structural genes

Question 2 of 18

3. The DNA-binding protein that initiates the transcription of bacterial genes is called a/an:

Promoter

Sigma Factor

Operator

Repressor

Question 3 of 18

4. Synthesis of mRNA on DNA template is:

Bidirectional

Unidirectional with the help of primer

Unidirectional

Bidirectional with help of primer

Question 4 of 18

5. Zinc finger protein and helix-turn-helix proteins are:

Members of metal binding proteins

Subunits of RNA polymerases

Types of DNA-binding proteins

Involved in the control of translation

Question 5 of 18

6. A series of genes that are transcriptionally regulated in trans by DNA—binding proteins are called a/an:

Repressor

Operon

Transcriptor

Promoter

Question 6 of 18

7. Binding of a given sigma factor depends of the:

Recognition of the length and spacing of promoter consensus sequences

Length of the transcription unit

Interaction with core enzyme

Distance of the translational start codon

Question 7 of 18

8. Which of the following statement about transcription is correct?

The RNA polymerase enzyme moves along the template strand of the DNA in a 5’ to 3’ direction

The RNA polymerase enzyme moves along the sense strand of the DNA in a 5’ to 3’ direction

RNA synthesis occurs in the 3’ to 5’ direction

The transcribed RNA is complementary to the non template strand

Question 8 of 18

9. How many different types of polypeptide subunits are present in RNA polymerase of E.coli?

Two

Three

Five

Four

Question 9 of 18

10. Alternative splicing can give rise to transcripts that differ in:

The coding region of the mRNA

The 5’ untranslated region of the mRNA

The 3’ untranslated region of the mRNA

All of these

Question 10 of 18

11. Mark the correct statements:

Transcription is a process that yields, semi-conservatively, two identical strands of DNA

DNA-dependent DNA polymerases are multi-subunit enzymes responsible for DNA transcription

Bacterial transcripts (mRNAs) are polygenic

Sigma factors guide the post-transcriptional modification of eukaryotic hmRNAs to mRNAs

Question 11 of 18

12. Mark all true statements:

(A) exons are found in the same order in the genome

(B) all cells in the human body have the same set of genes

(D) all cells in the human body splice mRNAs for each gene in the same way

C and D

A and D

A and B

B and C

Question 12 of 18

13. Catabolite activator protein (CAP) acts as:

Co-repressor

Apo repressor

Inducer

Apo inducer

Question 13 of 18

14. Tryptophan operon in E.coli is an example of:

Positively regulated operon

Repressible operon

All of these

Inducible operon

Question 14 of 18

15. Term ‘Homeobox’ was used by:

Goldberg

Walter Gehring

Dr. Hogness

Lewis

Question 15 of 18

16. Which one of the following statements about the tryptophan (trp) operon is true?

The trp repressor, like the lac repressor, is a tetramer of identical subunits

The trp repressor is a product of the trp operon

The trp repressor binds to tryptophan

The RNA product of the trp operon is very stable

Question 16 of 18

17. Bacteria utilize glucose first, even if other sugars are present, through a mechanism called:

Enzyme repression

Glucose utilization

Operon repression

Catabolite repression

Question 17 of 18

18. Regulation of polygenic transcription in prokaryotes can be at the level of:

RNA-polymerase holoenzyme recruitment to DNA (sigma factor specificity for promoters)

Enhancer binding protein-induced isomerization of the binary complex (DNA:Es)

All of these

Repressor and antitermination of transcrihtion

Question 18 of 18

Test Name	Gene Expression and Regulation Test
Subject	Biology
Test Type	Mcqs
Total Question	18
Total Marks	36
Total Time	18
Test Help For	Biology For All Grades General Knowledge Everyday Science CBSE Exam Medical Admission Entrance Test

Test By Subject	Science
Test By Topics	Biology Subject

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